Mixoma odontogénico: caso clínico y revisión de la literatura
Palabras clave:
Mixoma odontogénico, tumores odontogénicos, fibroblastos, mixoideResumen
El mixoma odontogénico (MO) es una neoplasia intraósea benigna de crecimiento lento localmente agresiva que deriva del tejido mesenquimatoso del germen dentario. Representa del 3 al 20% de todos los tumores odontogénicos. Tiene una predilección por el genero femenino entre la segunda y cuarta década de la vida. Histopatológicamente presenta células ahusadas y estrelladas embebidas en una matriz extracelular mixoide. Radiográficamente presenta varios diagnósticos diferenciales y su tratamiento va desde enucleación y legrado hasta cirugía radical, extirpando tejidos adyacentes.
El propósito de este trabajo es presentar el caso clínico de un paciente femenino de 31 años con diagnóstico compatible con mixoma odontogénico localizado en el cuerpo mandibular y rama ascendente derecha.
Citas
Wankhedkar D, Patankar S, Gokul S, Sharma S. Odontogenic myxoma in an 8-year-old girl: A case report with review of literature. J Oral Maxillofac Pathol. 2019;23(Suppl 1):83–86.
Ram H, Mehta G, Kumar M, Lone P. Odontogenic myxoma in a 52-year-old woman. BMJ Case Rep 2014; 2014: bcr2013202416.
Kumar, N, Kohli, M, Pandey, S, Agarwal, P. Odontogenic Myxoma. J Maxillofac Oral Surg. 2014;13(2): 222-226.
Liu Y, Han B, Yu T, Li L. A large odontogenic myxoma of the bilateral maxillae: A case report. Oncol Lett. 2014;8(3):1328–1332.
Shivashankara, C, Nidoni, M, Patil, S, Shashikala, K.T. Odontogenic myxoma: A review with report of an uncommon case with recurrence in the mandible of a teenage male. Saudi Dent J. 2017;29(3): 93-101.
Barnes L., Eveson J.W., Reichart P., Sidransky D. (Eds.): World Health Organization Classification of Tumours. Pathology and Genetics of Head and Neck Tumours. IARC Press: Lyon 2005.
Miranda Rius J, Nadal A, Lahor E, Mtui B, Brunet L. Unusual presentation of localized gingival enlargement associated with a slow-growing odontogenic myxoma. Int J Oral Sci. 2013;5(3):172–175.
Wang, K, et al. Characteristic features of the odontogenic myxoma on cone beam computed tomography. Dentomaxillofac Radiol. 2017;46 (2).
Kauke, M, safi, A.F, Kreppel, M, Grandoch, A, Nickenig, H.J. Size distribution and clinicoradiological signs of aggressiveness in odontogenic myxoma—three-dimensional analysis and systematic review. Dentomaxillofac Radiol. 2018;47(2): 20170262.
Kanitkar S, Kamat M, Tamagond S, Varekar A, Datar U. Peripheral odontogenic myxoma in a 12-year-old girl: a rare entity. J Korean Assoc Oral Maxillofac Surg. 2017;43(3):178–181.
Lahey, E, Woo, S.B, Park, H.K. Odontogenic Myxoma with Diffuse Calcifications: A Case Report and Review of the Literature. Head Neck Pathol. 2013;7(1): 97–102.
Dalbo Contrera Toro M, Siqueira Barreto I, Amstalden EM, Takahiro Chone C, Nizam Pfeilsticker L. Odontogenic Myxoma in Children: A Case Report and Literature Review. Case Rep Oncol Med. 2016;2016:9017421.
Lin YL, Basile JR. A case of odontogenic myxoma with unusual histological features mimicking a fibro-osseous process. Head Neck Pathol. 2010;4(3):253–256.
Sato H, Kurihara Y, Shiogama S, et al. Long-Term Follow-Up after Conservative Surgical Treatment of Odontogenic Myxoma: A Case Report and Literature Review. Case Rep Dent. 2019;2019:1634842.
Nonaka, C.F, Augusto Vianna Goulart Filho, J, Cristina da Costa Miguel, M, Batista de Souza, L, Pereira Pinto, L. Immunohistochemical expression of matrix metalloproteinases 1, 2, and 9 in odontogenic myxoma and dental germ papilla. Pathol Res Pract. 2009;205(7): 458-65.
González-Galván MC, Mosqueda-Taylor A, Bologna-Molina R, Setien-Olarra A, Marichalar-Mendia X, Aguirre-Urizar JM. Evaluation of the osteoclastogenic process associated with RANK / RANK-L / OPG in odontogenic myxomas. Med Oral Patol Oral Cir Bucal. 2018;23(3):e315–e319.
Andrade, FR, Sousa, DP, Mendonça, EF, Silva, TA, Lara, VS, & Batista, AC. Expression of bone resorption regulators (RANK, RANKL, and OPG) in odontogenic tumors. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106:548-55.
Bologna Molina, R, Mosqueda Taylor, A, Domínguez Malagón, H, Salazar Rodríguez, S, Tapia, G. Immunolocalization of VEGF-A and orosomucoid-1 in odontogenic myxoma. Rom J Morphol Embryol. 2015;56(2): 465-73.
